I’ve written hundreds of articles and several books, and I’m known for readable but heavily referenced analysis, with a touch of sass. • more about me • more about Pain This article needs to be updated.
Although it is accurate as far as it goes, it no longer goes far enough, and lacks modern perspective.
~ the prescription and widespread use of old-generation (SSRI class) anti-depressant medications such as Prozac, Zoloft, Paxil, Celexa and Luvox.
I cannot condemn it: I am not qualified to make that judgement.
Antidepressants are a popular treatment choice for depression.
Although antidepressants may not cure depression, they can reduce symptoms. But if it doesn't relieve your symptoms or it causes side effects that bother you, you may need to try another.
Indeed, there are documented cases of these companies successfully: This is no surprise given the amount of money and conflicts of interest involved. Finally, the scientific rationale for anti-depressants is not, it turns out, very good at all.
Credible criticism first came to public attention when David Healy, a professor of psychiatry who lost his job for speaking out about the undeniable risk that SSRIs cause a small percentage of patients to kill themselves, which had not yet been addressed in the scientific literature.3 In January 2008, the evidence resulted in a particularly underwhelming picture of the efficacy of these drugs, which appear to be no more effective than sugar pills for most depression7 — though they may be modestly effective for severe depression.89 This is not a I have a personal history with so-called “clinical” depression and bipolar disorder.
I always knew or suspected that they have numerous alarming side effects, that they are marketed aggressively by some of the most profitable and unaccountable corporations in the world, and that their usage does bad.
I assumed that their side effects were more or less as reported in drug references, that the manufacturers’ power to obscure the facts is mitigated by government agencies, and that the physiological rationale for the drugs is at least intelligible.
The trouble with SSRI drugs is old news now, and focusing on them here overshadows more relevant, recent developments in treatment for depression.
Evidence now shows that generation anti-depressant medications, like escitalopram and sertraline, are probably more safe and more effective than older and better-known SSRI,1 and this may (Even as evidence accumulates that cognitive behavioural therapy, probably the most common modern form of psychotherapy, may not be as effective as once hoped.2 Sigh.) The article will remain available as-is until I can revise it, or for another year or two, whichever comes first.
As a health care professional, I have had the opportunity to learn otherwise.